Metastatic follicular thyroid carcinoma to the mandible: A case report

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Metastatic follicular thyroid carcinoma to the mandible: A case report

Ajura AJ, Rohana S, Lau SH: Metastatic follicular thyroid carcinoma to the mandible: A case report. Mal. J. Oral Maxillofac. Surg. 2009; 7: 15–18.

Abstract: Metastatic tumours involving the oral cavity are rare with primary sites originating from the breast, lung, prostate, rectum and thyroid. Metastasis of follicular thyroid carcinoma to the oral cavity is not very frequent with only a few cases reported in the literature. A case of metastatic follicular carcinoma of the thyroid to the mandible in a 63 year old female Malay is presented. Patient had been diagnosed with advanced thyroid carcinoma with bones and lung metastases. The patient was referred for evaluation of a painless, soft, lobulated growth measuring 2.5 x 3.0 cm on the lower left edentulous alveolar region which was noted for a month duration. Orthopantomogram view revealed a large radiolucency extending from the distal of lower left third molar tooth to the left premolar- canine region. A biopsy of the growth was performed, and metastatic follicular carcinoma of thyroid origin was diagnosed. Immmunohistochemistry was carried out and showed the tumour cells were positive for thyroglobulin. Patients presenting with growth seen intra-orally and/or presence of radiolucent lesion of the jaw bones noted radiographically, and with a history of malignancy should be investigated for the high possibility of a metastatic tumour.